User:Hkhan11/Antipsychotic

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Lead[edit]

Antipsychotics, also known as neuroleptics, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders.  They are also the mainstay together with mood stabilizers in the treatment of bipolar disorder.

The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, and tardive akathisia. Prevention of these adverse effects is possible through concomitant medication strategies or using including use of beta-blockers. Currently, treatments for the tardive diseases are not well established.[1]

First-generation antipsychotics (e.g. chlorpromazine), known as typical antipsychotics, were first introduced in the 1950s, and others were developed until the early 1970s. Second-generation antipsychotics, known as atypical antipsychotics, were introduced firstly with clozapine in the early 1970s followed by others (e.g. risperidone). Both generations of medication block receptors in the brain for dopamine, but atypicals tend to act on serotonin receptors as well. Neuroleptic, originating from Greek: νεῦρον (neuron) and λαμβάνω (take hold of)—thus meaning "which takes the nerve"—refers to both common neurological effects and side effects.

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Benefits[edit]

There are benefits for using antipsychotics to treat many psychiatric disorders, as many antipsychotics are designed for to alleviate symptoms and help prevent relapses of episodes. Studies have shown that the longer treatment is not given, the greater the symptoms and episodes occur for that specific disorder.[2]


References[edit]

  1. ^ Stroup, T. Scott; Gray, Neil (2018-10). "Management of common adverse effects of antipsychotic medications". World Psychiatry. 17 (3): 341–356. doi:10.1002/wps.20567. ISSN 1723-8617. PMC 6127750. PMID 30192094. {{cite journal}}: Check date values in: |date= (help)
  2. ^ "Benefits of Antipsychotics Outweigh Risks, Find Experts". Columbia University Department of Psychiatry. 2017-05-12. Retrieved 2022-11-19.


Response to peer review: After reading my peer reviews, I will be making some significant changes to my article. When I read eresha8's review, she had suggested that I cut down the portion of the lead. As I read back through the lead, the lead is heavily detailed, and does need to be cut down to allow for a general basis of what the article will be. In union, most of my peer reviews say that the lead was confusing, and going from place to place, so I plan on leaving a brief history of antipsychotics. I was also suggested to add images, as the edits I have right now are all words.