User contributions for Stal potaten
A user with 42 edits. Account created on 7 April 2011.
23 July 2021
- 13:0313:03, 23 July 2021 diff hist +1,505 Pleiotropy Added section on Polygenic traits, including illustration of overlap matrix.
4 May 2021
- 15:4815:48, 4 May 2021 diff hist +37 m Non-coding DNA →Evidence from Polygenic Scores and GWAS: Updated reference and fixed links
3 May 2021
- 15:5615:56, 3 May 2021 diff hist +1,137 Non-coding DNA Added comment on non-coding variants in GWAS with reference.
- 15:3815:38, 3 May 2021 diff hist +38 m Non-coding DNA →Evidence from Polygenic Scores: Added link to Polygenic score page
- 15:2115:21, 3 May 2021 diff hist +2,045 Non-coding DNA Added subsection "Evidence from Polygenic Scores" about importance of non-genic regions to polygenic prediction.
28 April 2021
- 14:5014:50, 28 April 2021 diff hist −193 m Polygenic score Removed flags
14 April 2021
- 16:1616:16, 14 April 2021 diff hist +28 m Polygenic score Typos
- 16:0416:04, 14 April 2021 diff hist +493 Polygenic score Added some layman explanation in the description of the first figure (PRS illustration).
- 15:4815:48, 14 April 2021 diff hist −44 m Polygenic score →Importance of sample size: Reworded figure description
- 15:4715:47, 14 April 2021 diff hist +67 m Polygenic score →Importance of sample size: included ref-tag
- 15:4615:46, 14 April 2021 diff hist +637 Polygenic score Added figure for sample size dependence
- 15:4215:42, 14 April 2021 diff hist +69 m File:PGSPredictionPerformance VS sampleSize RabenLelloEtAl.svg →Summary: Added comment about using LASSO
- 15:3215:32, 14 April 2021 diff hist +776 N File:PGSPredictionPerformance VS sampleSize RabenLelloEtAl.svg {{Information |Description = PGS predictor performance increases with the dataset sample size available for training. Here illustrated for hypertension, hypothyroidism and type 2 diabetes. The x-axis labels number of cases (i.e. samples with the disease) present in the training data and uses a logarithmic scale. The entire range is from 1,000 cases up to over 100,000 cases. The numbers of controls (i.e. samples without the disease) in the training data were much larger than the numbers of cas...
- 14:5314:53, 14 April 2021 diff hist −11 m Polygenic score Fixed vertical spacing
- 14:4714:47, 14 April 2021 diff hist +2,811 Polygenic score →In humans: added section on sample size dependence
- 13:4013:40, 14 April 2021 diff hist −1 m Polygenic score →Examples of disease prediction: Typo.
- 13:3813:38, 14 April 2021 diff hist +1,570 m Polygenic score Fixed typos; Extended paragraph on embryonic genotyping and added references.
- 13:0013:00, 14 April 2021 diff hist −1 m Polygenic score →Examples of disease prediction: typo
13 April 2021
- 22:5922:59, 13 April 2021 diff hist +546 Talk:Polygenic score Added overall description of my series of edits in April 2021.
- 22:5222:52, 13 April 2021 diff hist +184 m Talk:Polygenic score →Unclear sentence: Discussion seems resolved to me.
- 22:4422:44, 13 April 2021 diff hist +4,961 Polygenic score Added continuous traits to human prediction performance; added subsection for human disease prediction performance; added sentence and references for proponents of embryo selection; reorganized section "Prediction performance"; minor typo fixes.
- 12:3312:33, 13 April 2021 diff hist 0 m Polygenic score →In humans: Fixed typo
- 12:1412:14, 13 April 2021 diff hist 0 m Polygenic score Fixed faulty reference tag
- 00:3000:30, 13 April 2021 diff hist +337 m Polygenic score Added info on utility of PRS for risk outliers.
- 00:0600:06, 13 April 2021 diff hist +6 m Polygenic score →Pruning and thresholding: fixed typo
- 00:0500:05, 13 April 2021 diff hist +32 m Polygenic score →Pruning and thresholding: Adjusting math formatting
12 April 2021
- 23:5123:51, 12 April 2021 diff hist +43 m Polygenic score →Pruning and thresholding: Added common numeric value for genome-wide significance.
- 23:4823:48, 12 April 2021 diff hist +11,736 Polygenic score Added some explanatory language and extended the introduction with machine learning and current state in the field; added sections "Validation methods", "Research on clinical applications", "Genetic Architecture"; added many references.
7 March 2017
- 15:0215:02, 7 March 2017 diff hist +13 m Complex projective space →Construction: Adding extra space between coordinates for increased readability.
- 15:0015:00, 7 March 2017 diff hist +24 m Complex projective space →Construction: Adding extra space between coordinates for increased readability.
16 July 2014
3 May 2014
- 08:1008:10, 3 May 2014 diff hist +1 m Kac–Moody algebra added a missing white space
26 April 2014
- 09:3109:31, 26 April 2014 diff hist 0 m Complexification (Lie group) spell correction "seem" -> "seen"
23 February 2014
- 09:2309:23, 23 February 2014 diff hist 0 m Volume element →Volume element of manifolds: Spelling of Civita
- 09:2209:22, 23 February 2014 diff hist +66 m Volume form →Riemannian volume form: Added explanation of epsilon.
- 09:1809:18, 23 February 2014 diff hist −4 m Volume element →Volume element of manifolds: Added wikilink
- 09:1509:15, 23 February 2014 diff hist +40 Volume element →Volume element of manifolds
- 09:0309:03, 23 February 2014 diff hist +12 Volume element →References
- 09:0109:01, 23 February 2014 diff hist +238 Volume element →Volume element of manifolds: Added that the volume element is the Levi-Cevita tensor
7 December 2013
- 13:5613:56, 7 December 2013 diff hist +2 m Non-linear sigma model Added the variable name "T" in the description lessening the dependence of the introductory sentences.
